![]() ![]() ![]() There, his focus on ultraviolet mutation patterns allowed his laboratory and fellow Yale Cancer Center scientists to identify the genes mutated by sunlight in causing skin cancer.īecause skin cancers are as frequent as all other cancers combined, Brash’s research has a global impact. In 1989, Brash joined the School of Medicine faculty at Yale University, where he is a senior research scientist and clinical professor of therapeutic radiology. Upon joining the staff of the National Cancer Institute, he identified the particular form of DNA damage responsible. During postdoctoral training in molecular genetics and cancer genetics at the Harvard School of Public Health and Harvard Medical School, he showed that mutations occur at the site of UV-induced DNA damage. Brash worked to explain the steps through which sunlight causes skin cancer, as well as sunlight’s role in triggering protective mechanisms. ![]()
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